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An expert panel hosted by
Sequencing immune-based therapies in B-cell malignancies
with Ulric Jäger, Sagar Lonial, and Krina Patel
Saturday, June 15 | 18:00-19:30 CEST
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On 7 January 2019, Magdalena Klanova, from Charles University, First Faculty of Medicine, Prague, CZ, and colleagues, published in Blood a secondary analysis from the phase III trial GOYA (NCT01287741) were diffuse large B-cell lymphoma (DLBCL) were treated with either obinutuzumab or rituximab, plus cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP; G-CHOP versus R-CHOP).
The aim of this analysis was to investigate the impact of cell-of-origin (COO), central nervous system (CNS)-International Prognostic Index (IPI), and BCL2/MYC double-expression on CNS relapse in these patients. The primary endpoint of this retrospective analysis was time to CNS relapse.
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