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Sequencing immune-based therapies in B-cell malignancies
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Improving safety and efficacy of brentuximab vedotin, nivolumab, and AD for advanced stage cHL.
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During the 64th American Society of Hematology (ASH) Annual Meeting and Exposition, the Lymphoma Hub spoke with Hun Lee, MD Anderson Cancer Centre, Texas, US. We asked about improving the safety and efficacy of combination treatment with brentuximab vedotin, nivolumab, adriamycin, and dacarbazine in patients with advanced-stage classic Hodgkin lymphoma.
Improving safety and efficacy of brentuximab vedotin, nivolumab, and AD for advanced stage cHL.
Lee discusses the long-term toxicities associated with prolonged chemotherapy treatment and findings from a study of combination treatment with brentuximab vedotin, nivolumab, adriamycin, and dacarbazine in patients with advanced-stage classic Hodgkin lymphoma. Lee then highlights the promising complete remission rates, progression-free survival, duration of remission, International Prognostic Scores, manageable safety profile, and overall response rates from a 12-month follow-up of the study.
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