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In December, 2016, Ralf U. Trappe from the Department of Internal Medicine, DIAKO Hospital Bremen, Germany, and colleagues published the results of an international, multi-center, phase II prospective study exploring response to rituximab induction treatment as a prognostic biomarker and risk stratification method in Post-Transplant Lymphoproliferative Disorder (PTLD) after Solid Organ Transplantation (SOT). The study, published in the Journal of Clinical Oncology, recruited 152 patients with CD20+ PTLD in the intention to treat population.
The authors concluded that in PTLD rituximab consolidation is better than induction alone, and that this method of treatment is feasible, effective and safe for adult patients with CD20+ PTLD after SOT.
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