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Sequencing immune-based therapies in B-cell malignancies
with Ulric Jäger, Sagar Lonial, and Krina Patel
Saturday, June 15 | 18:00-19:30 CEST
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A comprehensive safety analysis of venetoclax monotherapy was published in Clinical Cancer Research on 12 June 2018 by Matthew Davids, Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, and colleagues. The study evaluated patients with relapsed/refractory (R/R) chronic lymphocytic leukemia (CLL) based on the 2008 iwCLL criteria.
The authors found from this analysis that venetoclax monotherapy was well tolerated with patients with R/R CLL. They recommended that standardized ramp-up dosing and risk-adapted prophylaxis and monitoring can help prevent TLS risk.
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